Current Research Trials
NARCOLEPSY
Brilliance 302 (Narcolepsy Type 1) and Brilliance 303 (Narcolepsy Type 2)
Struggling with excessive daytime sleepiness or sudden sleep attacks?
The Brilliance study is evaluating an investigational medication for adults living with narcolepsy, a neurological sleep disorder that can cause:
Overwhelming daytime sleepiness
Sudden sleep episodes
Difficulty staying alert during daily activities
Researchers are studying whether this treatment may help:
Improve wakefulness during the day
Reduce unplanned sleep episodes
Support better daily functioning and quality of life
You may qualify if you:
Have been diagnosed with narcolepsy type 1 or type 2
Experience excessive daytime sleepiness
Are looking for additional treatment options
What participation involves:
Study medication (oral or other form depending on protocol)
Sleep assessments and symptom tracking
Regular visits with a clinical research team
Participants receive:
Study-related care at no cost
Close monitoring by sleep specialists
Compensation for your time
Interested? Email us at research@tricoastalsleep.com or click here.
OBSTRUCTIVE SLEEP APNEA
AMAZE 3 and 4 Studies (Obstructive Sleep Apnea + Obesity)
Tired of your obstructive sleep apnea symptoms - with or without CPAP?
The AMAZE studies are researching an investigational medication for adults with obstructive sleep apnea (OSA) who are also living with overweight or obesity.
OSA occurs when the airway becomes blocked during sleep, leading to:
Loud snoring
Interrupted breathing
Daytime fatigue and low energy
This study is evaluating whether a medication that targets weight and metabolic pathways may help:
Reduce the severity of sleep apnea
Improve breathing during sleep
Support meaningful weight loss
You may qualify if you:
Have been diagnosed with obstructive sleep apnea
Have a BMI ≥27
Participants can either have no treatment or currently use PAP therapy; either option is eligible for the study!
What makes this study different:
Investigational medication aimed at the root cause of OSA (weight-related airway obstruction)
Potential alternative or complement to CPAP
Participants receive:
Study-related care at no cost
Counsel by a dietician
Sleep evaluations and health monitoring
Compensation for your time and travel
Interested? Email us at research@tricoastalsleep.com or click here.
SHIFT WORK DISORDER
SUNOSI® (Solriamfetol) Study for Shift Work Sleep Disorder
Working nights or rotating shifts and struggling to stay awake?
You may qualify for a clinical research study evaluating SUNOSI® (solriamfetol), an FDA-approved medication being studied to help people with Shift Work Sleep Disorder (SWSD) improve wakefulness during their work hours.
Shift Work Sleep Disorder can affect people who work non-traditional hours, leading to:
Excessive sleepiness during night shifts
Difficulty staying alert on the job
Fatigue that impacts performance and safety
This study is evaluating whether SUNOSI® may help:
Improve wakefulness during scheduled work hours
Reduce excessive daytime or nighttime sleepiness
Support better functioning during shift-based schedules
You may qualify if you:
Work overnight, early morning, or rotating shifts
Regularly experience trouble staying awake during work hours
Are otherwise generally healthy or meet study-specific criteria
What to expect:
Study medication (SUNOSI® or placebo)
Wakefulness and sleep assessments
Regular visits with a clinical research team
Participants receive:
Study-related care at no cost
Close monitoring by medical professionals
Compensation for time and travel
Why participate?
Access to a medication already approved for other sleep disorders, now being studied for SWSD
Opportunity to improve alertness during work hours
Help advance research for people working non-traditional schedules
Interested? Email us at research@tricoastalsleep.com or click here.